Bleeding Profile Weight Data Expert Opinion Videos
ORTHO TRI-CYCLEN® LO minimizes unexpected bleeding and provides predictable periods1

Approximately 50% fewer women experienced breakthrough bleeding and spotting on ORTHO TRI-CYCLEN® LO than those on a 20-mcg monophasic comparator*1



Statistical differences in BTB/S occurred in all of the first 6 cycles (P<0.05)1

*A pivotal, randomized, multicenter study comparing the ORTHO TRI-CYCLEN® LO regimen with 20-mcg monophasic comparator regimen; two thirds of participants received study drug for 6 cycles and one third for 13 cycles.
†Valid on-therapy cycle evaluation.
    References:
  1. Hampton RM, Short M, Bieber E, et al. Comparison of a novel norgestimate/ethinyl estradiol oral contraceptive (Ortho Tri-Cyclen Lo) with the oral contraceptive Loestrin Fe 1/20. Contraception. 2001;63:289-295.
  2. Data on file, Ortho-McNeil-Janssen Pharmaceuticals, Inc.
ORTHO TRI-CYCLEN® LO demonstrates a favorable bleeding profile regardless of weight *2

*A retrospective analysis of 25-mcg triphasic pill phase 3 BTB/S data by weight.1
†Valid on-therapy cycle evaluation.
    References: 1.
  1. Hampton RM, Short M, Bieber E, et al. Comparison of a novel norgestimate/ethinyl estradiol oral contraceptive (Ortho Tri-Cyclen Lo) with the oral contraceptive Loestrin Fe 1/20. Contraception. 2001;63:289-295.
  2. Hampton RM, Zhang HF, Barnowski C, Wan GJ. Bleeding patterns with mono- and triphasic low-dose ethinyl estradiol combined oral contraceptives. Poster presented at: 55th Annual Meeting of the American College of Obstetricians and Gynecologists; May 5-9, 2007; San Diego, Calif.
What do the experts say about cycle control?
Take a moment to review these short videos from a contraceptive expert.

Cycle bleeding
Lee P. Shulman, MD, FACOG, FACMG
Professor, Department of Obstetrics and Gynecology
Northwestern University, Feinberg School of Medicine
Ortho Women's Health & Urology™ Consultant Speaker Bureau Member


Bleeding by age and by weight
Lee P. Shulman, MD, FACOG, FACMG
Professor, Department of Obstetrics and Gynecology
Northwestern University, Feinberg School of Medicine
Ortho Women's Health & Urology™ Consultant Speaker Bureau Member

    Reference:
  1. Hampton RM, Short M, Bieber E, et al. Comparison of a novel norgestimate/ethinyl estradiol oral contraceptive (Ortho Tri-Cyclen Lo) with the oral contraceptive Loestrin Fe 1/20. Contraception. 2001;63:289-295.